LY367385


SMILES OC(=O)c1ccc(c(c1)C)[C@@H](C(=O)O)N
InChIKey SGIKDIUCJAUSRD-QMMMGPOBSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 209.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 5.9 5.9 5.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 4.72 4.98 5.1 ChEMBL
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 5.1 5.1 5.1 Guide to Pharmacology