(+)-MCPG
| SMILES | OC(=O)c1ccc(cc1)[C@@](C(=O)O)(N)C |
| InChIKey | DNCAZYRLRMTVSF-JTQLQIEISA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 3 |
| Rotatable bonds | 3 |
| Molecular weight (Da) | 209.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pKi | 3.8 | 3.8 | 3.8 | Guide to Pharmacology |
| mGlu3 | GRM3 | Human | Metabotropic glutamate | C | pKi | 3.8 | 3.8 | 3.8 | Guide to Pharmacology |
| mGlu7 | GRM7 | Human | Metabotropic glutamate | C | pKi | 3.2 | 3.2 | 3.2 | Guide to Pharmacology |
| mGlu2 | GRM2 | Rat | Metabotropic glutamate | C | pKi | 4.6 | 4.6 | 4.6 | Guide to Pharmacology |
| mGlu1 | GRM1 | Rat | Metabotropic glutamate | C | pKi | 3.8 | 3.8 | 3.8 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pIC50 | 3.7 | 3.7 | 3.7 | Guide to Pharmacology |
| mGlu1 | GRM1 | Human | Metabotropic glutamate | C | pIC50 | 5.37 | 5.37 | 5.37 | ChEMBL |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pIC50 | 5.37 | 5.37 | 5.37 | ChEMBL |
| TSH | TSHR | Human | Glycoprotein hormone | A | Potency | 5.4 | 5.4 | 5.4 | ChEMBL |