[Met]enkephalin


SMILES None
InChIKey YFGBQHOOROIVKG-FKBYEOEOSA-N
Sequence YGGFM

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 9.2 9.2 9.2 Guide to Pharmacology
κ OPRK Guinea pig Opioid A pKi 5.35 5.35 5.35 ChEMBL
μ OPRM Rat Opioid A pKi 7.56 7.63 7.7 ChEMBL
δ OPRD Human Opioid A pKi 8.7 8.83 8.96 ChEMBL
μ OPRM Human Opioid A pKi 7.72 7.72 7.72 ChEMBL
κ OPRK Rat Opioid A pKi 6.0 6.0 6.0 Guide to Pharmacology
NOP OPRX Guinea pig Opioid A pKi 6.56 6.56 6.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 7.4 7.4 7.4 Guide to Pharmacology
δ OPRD Mouse Opioid A pIC50 7.89 7.89 7.89 ChEMBL
μ OPRM Rat Opioid A pIC50 8.7 8.7 8.7 ChEMBL
μ OPRM Rat Opioid A pEC50 6.51 6.51 6.52 ChEMBL
δ OPRD Human Opioid A pEC50 7.33 8.44 8.99 ChEMBL
δ OPRD Human Opioid A pIC50 8.19 8.19 8.19 ChEMBL
μ OPRM Human Opioid A pIC50 7.89 7.89 7.89 ChEMBL
μ OPRM Human Opioid A pEC50 6.21 6.21 6.21 ChEMBL