methoxymethyl-MTEP


SMILES COCc1cncc(c1)C#Cc1csc(n1)C
InChIKey AWDRAHDWMICWJM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 244.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKd 7.7 7.7 7.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.5 7.5 7.5 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.33 7.74 8.15 ChEMBL