MF 498


SMILES CCOc1c2CN(C(=O)c2c(c2c1nccc2)OCC)c1ccc(cc1C)CS(=O)(=O)NC(=O)Cc1ccccc1OC
InChIKey WVLIUERFVJYBNY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 603.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKi 8.44 8.79 9.13 ChEMBL
DP1 PD2R Human Prostanoid A pKi 5.92 5.92 5.92 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 5.72 5.72 5.72 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 5.4 5.4 5.4 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 9.15 9.15 9.15 Guide to Pharmacology
FP PF2R Human Prostanoid A pKi 5.7 5.7 5.7 ChEMBL
TP TA2R Human Prostanoid A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database