Neurotensin


SMILES None
InChIKey PCJGZPGTCUMMOT-ISULXFBGSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NTS1 NTR1 Rat Neurotensin A pKi 8.2 9.1 10.0 Guide to Pharmacology
NTS1 NTR1 Rat Neurotensin A pKd 9.6 9.75 9.9 Guide to Pharmacology
NTS1 NTR1 Human Neurotensin A pKi 8.3 9.0 9.7 Guide to Pharmacology
NTS2 Q920Q5 Mouse Neurotensin A pIC50 8.5 8.6 8.7 Guide to Pharmacology
NTS2 Q920Q5 Mouse Neurotensin A pKd 8.6 8.6 8.6 Guide to Pharmacology
NTS2 NTR2 Rat Neurotensin A pIC50 8.649999999999999 8.65 8.65 Guide to Pharmacology
NTS2 NTR2 Human Neurotensin A pKi 8.8 8.8 8.8 Guide to Pharmacology
NTS1 NTR1 Mouse Neurotensin A pKi 9.77 9.77 9.77 ChEMBL
NTS1 NTR1 Mouse Neurotensin A pEC50 8.7 8.7 8.7 ChEMBL
NTS2 NTR2 Rat Neurotensin A pIC50 6.94 7.35 7.73 ChEMBL
NTS2 NTR2 Rat Neurotensin A pKi 7.55 7.65 7.72 ChEMBL
NTS1 NTR1 Rat Neurotensin A pEC50 10.4 10.4 10.4 ChEMBL
NTS1 NTR1 Rat Neurotensin A pKi 8.77 8.87 8.96 ChEMBL
NTS2 NTR2 Human Neurotensin A pKi 8.31 8.34 8.39 ChEMBL
NTS2 NTR2 Human Neurotensin A pEC50 6.96 6.96 6.96 ChEMBL
NTS1 NTR1 Human Neurotensin A pIC50 8.22 9.13 9.7 ChEMBL
NTS1 NTR1 Human Neurotensin A pEC50 6.51 8.47 9.64 ChEMBL
NTS1 NTR1 Human Neurotensin A pKi 8.48 8.88 9.57 ChEMBL
NTS1 NTR1 Human Neurotensin A pKd 9.23 9.26 9.29 ChEMBL
NTS1 NTR1 Mouse Neurotensin A pKi 8.6 8.6 8.6 PDSP Ki database