Ligand Data

Ligand

id 2647
Name neurotensin
SMILES None
InChIKey PCJGZPGTCUMMOT-ISULXFBGSA-N
Type peptide
Sequence XLYENKPRRPYIL
External Links
Structure pdb 3ZEV 4BUO 4BV0 4BWB 4XES 4XEE 5T04 7L0P 7L0Q 7L0R 7L0S

Structure

Properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
NTS1 NTR1 Mouse Neurotensin A (Rhodopsin) 2.0 2.0 2.0
NTS2 NTR2 Rat Neurotensin A (Rhodopsin) 18.5 40.4 114.0
NTS1 NTR1 Rat Neurotensin A (Rhodopsin) 1.1 1.4 1.7 0.0 0.0 0.0
NTS2 NTR2 Human Neurotensin A (Rhodopsin) 4.1 4.5 4.9 110 110 110
NTS1 NTR1 Human Neurotensin A (Rhodopsin) 0.2 1.3 6.0 0.2 63.2 310.0