cyproheptadine [2680]



cyproheptadine


SMILES CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1
InChIKey JJCFRYNCJDLXIK-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 0
Log P 4.698
Molecular weight (Da) 287.2
Stereochemistry info unspecified

Database connections

Model (Boltz2) 5-HT2A 5-HT2C H1
Ligand site mutations 5-HT2A 5-HT2C

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

cyproheptadine


Drug properties

Molecular type Lipid
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 10
Phase III 3
Phase IV 12

Database connections

Model (Boltz2) 5-HT2A 5-HT2C H1
Ligand site mutations 5-HT2A 5-HT2C

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score