dAVP [2746]
dAVP
| SMILES | NC(=O)CCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccc(O)cc2)NC(=O)CCSSCC(C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC1=O |
| InChIKey | NFLWUMRGJYTJIN-UHFFFAOYSA-N |
| Sequence | XYFQNCPRG |
| HELM | PEPTIDE1{[*C(=O)CCS* |$_R2;;;;;;_R3$|].(Y,[dY]).(F,[dF]).(Q,[dQ]).(N,[dN]).(C,[dC]).(P,[dP]).(R,[dR]).G.[am]}$PEPTIDE1,PEPTIDE1,1:R3-6:R3$$$V2.0 |
Chemical Properties
| Hydrogen bond acceptors | 15 |
| Hydrogen bond donors | 13 |
| Rotatable bonds | 19 |
| Log P | -4.342 |
| Molecular weight (Da) | 1068.4 |
| Stereochemistry info | unspecified |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
dAVP
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Distribution across phases (no. indications)
Phase I
3
Phase II
12
Phase III
6
Phase IV
12
Sankey plot
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Drug Information
| Target | Disease | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene | Protein | Receptor family | Ligand type | Class | Name | Phase | ICD11 | ATC | Association score |