cyproheptadine


SMILES CN1CCC(=C2c3ccccc3C=Cc3c2cccc3)CC1
InChIKey JJCFRYNCJDLXIK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 287.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations 5-HT2A 5-HT2C

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC2 ACTHR Mouse Melanocortin A pKd 9.1 9.1 9.1 Guide to Pharmacology
MC2 ACTHR Human Melanocortin A pKi 8.08 8.08 8.08 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 8.04 8.04 8.04 Drug Central
MC4 MC4R Human Melanocortin A pEC50 9.19 9.19 9.19 ChEMBL