myristic acid
SMILES | CCCCCCCCCCCCCC(=O)O |
InChIKey | TUNFSRHWOTWDNC-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 1 |
Hydrogen bond donors | 1 |
Rotatable bonds | 12 |
Molecular weight (Da) | 228.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Endogenous |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NOP | OPRX | Human | Opioid | A | pKd | 9.82 | 10.01 | 10.2 | Guide to Pharmacology |
NOP | OPRX | Human | Opioid | A | pKi | 9.7 | 10.05 | 10.4 | Guide to Pharmacology |
NOP | OPRX | Mouse | Opioid | A | pKi | 9.4 | 9.4 | 9.4 | Guide to Pharmacology |
NOP | OPRX | Rat | Opioid | A | pKd | 9.15 | 9.54 | 10.06 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pKi | 9.26 | 9.73 | 10.31 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pKd | 9.72 | 9.88 | 10.04 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 5.52 | 5.54 | 5.55 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 5.82 | 6.33 | 6.83 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 5.52 | 6.15 | 6.57 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NOP | OPRX | Human | Opioid | A | pEC50 | 8.4 | 9.1 | 9.8 | Guide to Pharmacology |
NOP | OPRX | Guinea pig | Opioid | A | pEC50 | 8.05 | 8.16 | 8.28 | ChEMBL |
NOP | OPRX | Rat | Opioid | A | pIC50 | 8.99 | 9.27 | 9.66 | ChEMBL |
NOP | OPRX | Rat | Opioid | A | pEC50 | 6.83 | 7.91 | 8.96 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pEC50 | 7.2 | 8.94 | 10.1 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pIC50 | 8.68 | 9.16 | 10.08 | ChEMBL |
κ | OPRK | Human | Opioid | A | pEC50 | 7.11 | 7.11 | 7.11 | ChEMBL |
NOP | OPRX | Mouse | Opioid | A | pEC50 | 7.45 | 7.91 | 8.27 | ChEMBL |