genistein
| SMILES | Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O |
| InChIKey | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 3 |
| Rotatable bonds | 1 |
| Molecular weight (Da) | 270.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CB1 | CNR1 | Human | Cannabinoid | A | pKi | 5.3 | 5.3 | 5.3 | PDSP Ki database |
| CB2 | CNR2 | Human | Cannabinoid | A | pKi | 8.28 | 8.28 | 8.28 | Drug Central |
| CB1 | CNR1 | Human | Cannabinoid | A | pKi | 8.28 | 8.28 | 8.28 | Drug Central |
| CB2 | CNR2 | Human | Cannabinoid | A | pKi | 5.3 | 5.3 | 5.3 | PDSP Ki database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GPR55 | GPR55 | Human | GPR18, GPR55 and GPR119 | A | pEC50 | 8.4 | 8.4 | 8.4 | Guide to Pharmacology |
| M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | Potency | 7.05 | 7.05 | 7.05 | ChEMBL |
| GPR55 | GPR55 | Human | GPR18, GPR55 and GPR119 | A | pEC50 | 8.08 | 8.08 | 8.08 | Drug Central |