pirenperone


SMILES Fc1ccc(cc1)C(=O)C1CCN(CC1)CCc1c(C)nc2n(c1=O)cccc2
InChIKey HXCNRYXBZNHDNE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 393.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 7.43 7.43 7.43 Guide to Pharmacology
μ OPRM Human Opioid A pKi 7.49 7.49 7.49 Guide to Pharmacology
δ OPRD Human Opioid A pKi 9.08 9.08 9.08 ChEMBL
δ OPRD Human Opioid A pKi 9.08 9.08 9.08 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.7 7.7 7.7 ChEMBL