N/OFQ-(1-13)-NH2


SMILES None
InChIKey RHMALYOXPBRJBG-CGUXNFSNSA-N
Sequence FGGFTGARKSARK

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.21 9.34 9.46 ChEMBL
NOP OPRX Human Opioid A pKi 10.1 10.25 10.4 Guide to Pharmacology
NOP OPRX Mouse Opioid A pKi 9.04 9.07 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 9.45 9.45 9.45 ChEMBL
NOP OPRX Human Opioid A pEC50 8.0 8.72 9.49 ChEMBL
NOP OPRX Rat Opioid A pEC50 6.24 6.64 7.29 ChEMBL
NOP OPRX Mouse Opioid A pEC50 7.94 7.95 7.96 ChEMBL