ONO-AE2-227


SMILES O=C(C(c1cccc2c1cccc2)C)Nc1ccccc1Cc1ccccc1C(=O)O
InChIKey BLJLWFKNTKAUDA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pKi 7.68 7.68 7.68 Guide to Pharmacology
EP4 PE2R4 Mouse Prostanoid A pKi 8.57 8.57 8.57 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pIC50 6.8 6.8 6.8 Guide to Pharmacology