furtrethonium


SMILES C[N+](Cc1ccco1)(C)C
InChIKey HEDXEAAVEOJUCR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 140.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Human Melanocortin A pKi 8.9 8.9 8.9 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pKi 8.5 8.65 8.8 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pKi 7.72 9.0 9.52 ChEMBL
MC1 MSHR Human Melanocortin A pKi 8.74 9.46 10.34 ChEMBL
MC3 MC3R Human Melanocortin A pKi 9.11 9.14 9.17 ChEMBL
MC5 MC5R Human Melanocortin A pKi 8.0 8.66 9.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pIC50 10.0 10.0 10.0 Guide to Pharmacology
MC5 MC5R Human Melanocortin A pIC50 9.0 9.0 9.0 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pIC50 7.85 8.96 9.82 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.05 9.27 10.77 ChEMBL
MC1 MSHR Human Melanocortin A pEC50 9.3 9.95 10.64 ChEMBL
MC1 MSHR Human Melanocortin A pIC50 9.29 9.29 9.29 ChEMBL
MC3 MC3R Human Melanocortin A pIC50 8.42 8.63 8.93 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 8.17 9.15 9.89 ChEMBL
MC5 MC5R Human Melanocortin A pIC50 8.66 8.9 9.07 ChEMBL
MC5 MC5R Human Melanocortin A pEC50 8.96 9.21 9.64 ChEMBL
MC3 MC3R Mouse Melanocortin A pEC50 7.12 9.76 10.2 ChEMBL
MC3 MC3R Mouse Melanocortin A pIC50 8.09 8.25 8.38 ChEMBL
MC3 MC3R Rat Melanocortin A pEC50 10.0 10.0 10.0 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 6.92 9.48 10.01 ChEMBL
MC4 MC4R Mouse Melanocortin A pIC50 8.38 8.73 8.96 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 7.92 10.42 11.0 ChEMBL
MC1 MSHR Mouse Melanocortin A pIC50 9.51 9.52 9.54 ChEMBL
MC5 MC5R Mouse Melanocortin A pEC50 6.77 9.71 10.52 ChEMBL
MC5 MC5R Mouse Melanocortin A pIC50 6.85 6.85 6.85 ChEMBL