pentylthio-TZTP


SMILES CCCCCSc1nsnc1C1=CCCN(C1)C
InChIKey LRTWCQHCJKYNPS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 283.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.6 8.6 8.6 Guide to Pharmacology
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.9 7.9 7.9 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.1 8.1 8.1 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.7 8.7 8.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A pIC50 8.32 8.47 8.62 ChEMBL