phentolamine



phentolamine


SMILES Cc1ccc(N(CC2=NCCN2)c2cccc(O)c2)cc1
InChIKey MRBDMNSDAVCSSF-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 281.2

Database connections

Ligand site mutations α1A α1B α2A

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

phentolamine


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 6
Phase II 6
Phase III 6
Phase IV 12

Database connections

Ligand site mutations α1A α1B α2A

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score