RS67506


SMILES COc1cc(N)c(cc1C(=O)CCC1CCN(CC1)CCNS(=O)(=O)C)Cl
InChIKey UATDVRSFFGFTAI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 417.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Human Adrenoceptors A pKi 6.75 6.75 6.75 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 6.74 6.74 6.74 PDSP Ki database
β2 ADRB2 Human Adrenoceptors A pKi 6.74 6.74 6.74 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Guinea pig Adrenoceptors A pEC50 8.21 8.21 8.21 ChEMBL
β2 ADRB2 Human Adrenoceptors A pIC50 6.48 6.48 6.48 ChEMBL
TA1 TAAR1 Mouse Trace amine A pEC50 4.8 4.8 4.8 Guide to Pharmacology