etelcalcetide [3268]



etelcalcetide


SMILES CC(=O)N[C@H](CSSC[C@H](N)C(=O)O)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(N)=O
InChIKey ANIAZGVDEUQPRI-ZJQCGQFWSA-N
Sequence CARRRAR
HELM PEPTIDE1{[ac].[dC].[dA].[dR].[dR].[dR].[dA].[dR].[am]}|PEPTIDE2{C}$PEPTIDE2,PEPTIDE1,1:R3-2:R3$$$

Chemical Properties

Hydrogen bond acceptors 16
Hydrogen bond donors 18
Rotatable bonds 36
Log P -8.067
Molecular weight (Da) 1047.5
Stereochemistry info unspecified

Database connections

Structure pdb 7M3G
Model (Boltz2) CaS

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

etelcalcetide


Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 1

Database connections

Structure pdb 7M3G
Model (Boltz2) CaS

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score