ecopipam


SMILES CN1CCc2c([C@@H]3[C@@H]1CCc1c3cccc1)cc(c(c2)Cl)O
InChIKey DMJWENQHWZZWDF-PKOBYXMFSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 313.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pKi 7.5 7.5 7.5 Guide to Pharmacology
TA1 TAAR1 Rat Trace amine A pKi 8.6 8.6 8.6 Guide to Pharmacology
TA1 TAAR1 Mouse Trace amine A pKi 8.7 8.7 8.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pEC50 7.23 7.23 7.23 ChEMBL
TA1 TAAR1 Human Trace amine A pEC50 7.3 7.3 7.3 Guide to Pharmacology
TA1 TAAR1 Rat Trace amine A pEC50 7.85 7.85 7.85 ChEMBL
TA1 TAAR1 Rat Trace amine A pEC50 7.9 7.9 7.9 Guide to Pharmacology
TA1 TAAR1 Mouse Trace amine A pEC50 8.52 8.52 8.52 ChEMBL
TA1 TAAR1 Mouse Trace amine A pEC50 8.5 8.5 8.5 Guide to Pharmacology