ronacaleret


SMILES O[C@@H](COc1cc(CCC(=O)O)cc(c1F)F)CNC(CC1Cc2c(C1)cccc2)(C)C
InChIKey FQJISUPNMFRIFZ-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CaS CASR Rat Calcium-sensing C pIC50 6.5 6.5 6.5 ChEMBL
CaS CASR Human Calcium-sensing C pIC50 6.84 6.84 6.84 ChEMBL
CaS CASR Human Calcium-sensing C pIC50 6.5 6.65 6.8 Guide to Pharmacology