WIN 51,708


SMILES C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@@H]2[C@]1(C)Cc1cn3c(nc1C2)nc1c3cccc1
InChIKey AIIXYCDTEGICEE-HZVAOYAWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 439.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 5.9 5.9 5.9 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 5.5 5.5 5.5 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKd 6.2 6.2 6.2 Guide to Pharmacology
M1 ACM1 Human Acetylcholine (muscarinic) A pKd 5.8 5.8 5.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database