(S)-4CPG


SMILES N[C@@H](c1ccc(cc1)C(=O)O)C(=O)O
InChIKey VTMJKPGFERYGJF-ZETCQYMHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 195.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pKi 4.08 4.08 4.08 ChEMBL
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 5.43 5.43 5.43 ChEMBL
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 5.4 5.4 5.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 4.19 4.48 5.0 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 4.6 4.6 4.6 Guide to Pharmacology