(1S,3R)-ACPD
| SMILES | OC(=O)[C@@H]1CC[C@@](C1)(N)C(=O)O |
| InChIKey | YFYNOWXBIBKGHB-FBCQKBJTSA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 3 |
| Rotatable bonds | 2 |
| Molecular weight (Da) | 173.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pKi | 4.2 | 4.2 | 4.2 | Guide to Pharmacology |
| mGlu7 | GRM7 | Human | Metabotropic glutamate | C | pKi | 3.05 | 3.05 | 3.05 | Guide to Pharmacology |
| mGlu3 | GRM3 | Rat | Metabotropic glutamate | C | pKi | 4.8 | 4.8 | 4.8 | Guide to Pharmacology |
| mGlu2 | GRM2 | Rat | Metabotropic glutamate | C | pKi | 5.0 | 5.2 | 5.4 | Guide to Pharmacology |
| mGlu1 | GRM1 | Rat | Metabotropic glutamate | C | pKi | 5.5 | 5.8 | 6.1 | Guide to Pharmacology |
| mGlu6 | GRM6 | Human | Metabotropic glutamate | C | pKi | 4.22 | 4.22 | 4.22 | ChEMBL |
| mGlu1 | GRM1 | Human | Metabotropic glutamate | C | pKi | 4.38 | 4.38 | 4.38 | ChEMBL |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pKi | 5.3 | 5.3 | 5.3 | ChEMBL |
| mGlu3 | GRM3 | Human | Metabotropic glutamate | C | pKi | 4.7 | 4.7 | 4.7 | Guide to Pharmacology |
| mGlu4 | GRM4 | Human | Metabotropic glutamate | C | pKi | 4.01 | 4.01 | 4.01 | ChEMBL |
| mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pKi | 4.82 | 4.82 | 4.82 | ChEMBL |
| mGlu8 | GRM8 | Human | Metabotropic glutamate | C | pKi | 4.35 | 4.35 | 4.35 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu6 | GRM6 | Human | Metabotropic glutamate | C | pEC50 | 4.7 | 4.7 | 4.7 | Guide to Pharmacology |
| mGlu8 | GRM8 | Human | Metabotropic glutamate | C | pEC50 | 4.4 | 4.4 | 4.4 | Guide to Pharmacology |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pIC50 | 5.7 | 5.7 | 5.7 | Guide to Pharmacology |
| mGlu6 | GRM6 | Rat | Metabotropic glutamate | C | pEC50 | 4.2 | 4.2 | 4.2 | Guide to Pharmacology |
| mGlu8 | GRM8 | Rat | Metabotropic glutamate | C | pEC50 | 4.3 | 4.3 | 4.3 | Guide to Pharmacology |
| mGlu6 | GRM6 | Rat | Metabotropic glutamate | C | pEC50 | 4.22 | 4.22 | 4.22 | ChEMBL |
| mGlu6 | GRM6 | Human | Metabotropic glutamate | C | pEC50 | 4.09 | 4.09 | 4.09 | ChEMBL |
| mGlu1 | GRM1 | Human | Metabotropic glutamate | C | pEC50 | 4.66 | 4.84 | 5.03 | ChEMBL |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pEC50 | 4.75 | 5.12 | 5.7 | ChEMBL |
| mGlu3 | GRM3 | Human | Metabotropic glutamate | C | pEC50 | 4.52 | 4.52 | 4.52 | ChEMBL |
| mGlu4 | GRM4 | Human | Metabotropic glutamate | C | pEC50 | 4.41 | 4.41 | 4.41 | ChEMBL |
| mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pEC50 | 4.64 | 4.64 | 4.64 | ChEMBL |
| mGlu3 | GRM3 | Rat | Metabotropic glutamate | C | pEC50 | 5.1 | 5.1 | 5.1 | ChEMBL |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pEC50 | 4.3 | 4.59 | 4.82 | ChEMBL |
| mGlu2 | GRM2 | Rat | Metabotropic glutamate | C | pEC50 | 5.11 | 5.42 | 5.7 | ChEMBL |
| mGlu1 | GRM1 | Rat | Metabotropic glutamate | C | pEC50 | 4.3 | 4.54 | 4.82 | ChEMBL |
| mGlu4 | GRM4 | Rat | Metabotropic glutamate | C | pEC50 | 4.41 | 4.41 | 4.41 | ChEMBL |