Skf-83959

Chemical Properties

SMILES CN1CCc2c(C(C1)c1cccc(c1)C)cc(c(c2Cl)O)O
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight 317.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey JXMYTVOBSFOHAF-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 9.7 9.7 9.7 Guide to Pharmacology
D1 DRD1 Human Dopamine A pKi 8.71 8.86 8.93 ChEMBL
D1 DRD1 Human Dopamine A pEC50 9.7 9.7 9.7 ChEMBL
D1 DRD1 Rat Dopamine A pKi 7.93 7.93 7.93 PDSP KiDatabase
D2 DRD2 Rat Dopamine A pKi 5.04 5.04 5.04 PDSP KiDatabase
D3 DRD3 Human Dopamine A pKi 5.4 5.4 5.4 PDSP KiDatabase
D5 DRD5 Human Dopamine A pKi 7.12 7.12 7.12 PDSP KiDatabase
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 5.58 5.58 5.58 PDSP KiDatabase