5-oxo-ETE


SMILES CCCCC/C=C\C/C=C\C/C=C\C=C\C(=O)CCCC(=O)O
InChIKey MEASLHGILYBXFO-XTDASVJISA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 14
Molecular weight (Da) 318.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETB EDNRB Rat Endothelin A pKi 10.89 10.91 10.92 ChEMBL
ETA EDNRA Rat Endothelin A pKi 9.62 9.84 10.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETA EDNRA Human Endothelin A pIC50 7.5 7.8 8.1 Guide to Pharmacology