L742791


SMILES O[C@H](COc1ccc(cc1)O)CNCCc1ccc(cc1)NS(=O)(=O)c1ccc(cc1)I
InChIKey ZNTDIRUBXSTBGJ-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 568.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 8.06 8.06 8.06 ChEMBL
OX1 OX1R Human Orexin A pKd 8.35 8.35 8.35 ChEMBL
OX2 OX2R Human Orexin A pKi 6.3 6.3 6.3 ChEMBL
OX1 OX1R Human Orexin A pKi 7.7 7.7 7.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database