semaglutide
| SMILES | None |
| InChIKey | DLSWIYLPEUIQAV-CCUURXOWSA-N |
| Sequence | HAEGTFTSDVSSYLEGQAAKEFIAWLVRGRG |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Endogenous/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
| Structure pdb | 7KI0 |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GLP-1 | GLP1R | Human | Glucagon | B1 | pKd | 6.36 | 6.36 | 6.36 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GLP-1 | GLP1R | Human | Glucagon | B1 | pIC50 | 7.52 | 8.71 | 9.89 | ChEMBL |
| GLP-1 | GLP1R | Human | Glucagon | B1 | pEC50 | 10.73 | 10.73 | 10.73 | ChEMBL |
| GLP-1 | GLP1R | Human | Glucagon | B1 | pIC50 | 8.03 | 8.03 | 8.03 | Drug Central |
| GLP-1 | GLP1R | Human | Glucagon | B1 | pEC50 | 11.21 | 11.21 | 11.21 | Guide to Pharmacology |
| GLP-1 | GLP1R | Human | Glucagon | B1 | pIC50 | 9.42 | 9.42 | 9.42 | Guide to Pharmacology |