Tasosartan

Chemical Properties

SMILES Cc1nc(C)c2c(n1)N(Cc1ccc(cc1)c1ccccc1c1nn[nH]n1)C(=O)CC2
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight 411.2

Drug Properties

Type Small molecule
Endogenous No
Approved Yes
InChIKey ADXGNEYLLLSOAR-UHFFFAOYSA-N

Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pIC50 8.92 8.92 8.92 Guide to Pharmacology
AT1 AGTR1 Human Angiotensin A pIC50 7.42 7.46 7.5 ChEMBL