SKF 105854


SMILES CN1CCc2c3c(C1)c(Br)oc3ccc2Cl
InChIKey NYGANYRUZQPPGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 299.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 5.48 5.48 5.48 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.11 6.11 6.11 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.14 7.14 7.14 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.1 7.1 7.1 Guide to Pharmacology
α2A ADA2A Human Adrenoceptors A pKi 7.27 7.27 7.27 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 7.85 7.85 7.85 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.55 7.55 7.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database