imipramine
| SMILES | CN(CCCN1c2ccccc2CCc2c1cccc2)C |
| InChIKey | BCGWQEUPMDMJNV-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 4 |
| Molecular weight (Da) | 280.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKd | 7.3 | 7.55 | 7.8 | Guide to Pharmacology |
| CRF2 | CRFR2 | Mouse | Corticotropin-releasing factor | B1 | pKd | 9.0 | 9.05 | 9.1 | Guide to Pharmacology |
| CRF2 | CRFR2 | Rat | Corticotropin-releasing factor | B1 | pKd | 8.3 | 8.35 | 8.4 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |