SUVN-G3031


SMILES O=C(Nc1ccc(cc1)OC1CCN(CC1)C1CCC1)CN1CCOCC1
InChIKey LNXDUSQEXVQFGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 8.06 8.06 8.06 ChEMBL
H3 HRH3 Human Histamine A pKi 8.06 8.06 8.06 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 8.01 8.01 8.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pIC50 7.7 7.7 7.7 ChEMBL