[Gln8]GnRH [3692]
[Gln8]GnRH
| SMILES | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O |
| InChIKey | WPKQYFUSPONRAT-BXXNOCLASA-N |
| Sequence | XHWSYGLQPG |
| HELM | PEPTIDE1{[Glp].H.W.S.Y.G.L.Q.P.G.[am]}$$$$ |
Chemical Properties
| Hydrogen bond acceptors | 15 |
| Hydrogen bond donors | 15 |
| Rotatable bonds | 30 |
| Log P | -4.176 |
| Molecular weight (Da) | 1153.5 |
| Stereochemistry info | unspecified |
Database connections
| Model (AF2) | GnRH1 |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
[Gln8]GnRH
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Distribution across phases (no. indications)
Phase I
0
Phase II
0
Phase III
0
Phase IV
0
Database connections
| Model (AF2) | GnRH1 |