R-spondin-2


SMILES None
InChIKey None
Sequence QGNRWRRSKRASYVSNPICKGCLSCSKDNGCSRCQQKLFFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVEGCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDRANQ

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 6.54 6.54 6.54 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 9.52 9.52 9.52 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 9.52 9.52 9.52 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pKi 6.54 6.54 6.54 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pIC50 5.93 6.39 6.54 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 7.66 9.15 10.03 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 8.62 8.62 8.62 ChEMBL
CB1 CNR1 Rat Cannabinoid A pIC50 9.07 9.29 9.52 ChEMBL