Vilanterol


SMILES OCc1cc(ccc1O)[C@H](CNCCCCCCOCCOCc1c(Cl)cccc1Cl)O
InChIKey DAFYYTQWSAWIGS-DEOSSOPVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 16
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pEC50 6.4 6.4 6.4 ChEMBL
β3 ADRB3 Human Adrenoceptors A pEC50 6.1 6.1 6.1 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 9.4 9.4 9.4 ChEMBL
β1 ADRB1 Human Adrenoceptors A pEC50 8.19 8.19 8.19 Drug Central
β2 ADRB2 Human Adrenoceptors A pEC50 8.03 8.03 8.03 Drug Central
β3 ADRB3 Human Adrenoceptors A pEC50 8.21 8.21 8.21 Drug Central
β2 ADRB2 Human Adrenoceptors A pEC50 9.4 9.4 9.4 Guide to Pharmacology