GR 125,743 [3771]



GR 125,743


SMILES COc1ccc(NC(=O)c2ccc(-c3ccncc3)c(C)c2)cc1N1CCN(C)CC1
InChIKey GNOXPYACARZYMW-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Log P 4.070
Molecular weight (Da) 416.2
Stereochemistry info unspecified

Database connections

Ligand site mutations 5-HT1B
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

GR 125,743


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Ligand site mutations 5-HT1B

Compound is not listed as a drug.