GPCRdb

tegaserod

Agent/drug
Bioactivity

tegaserod

SMILES	CCCCCN=C(N)N/N=C/c1c[nH]c2ccc(OC)cc12
InChIKey	IKBKZGMPCYNSLU-RGVLZGJSSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	3
Rotatable bonds	7
Molecular weight (Da)	301.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Human	Adrenoceptors	A	pKi	5.79	5.79	5.79	ChEMBL
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.58	5.58	5.58	ChEMBL
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.79	5.79	5.79	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.55	5.55	5.55	ChEMBL
β₁	ADRB1	Human	Adrenoceptors	A	pKi	5.40	5.40	5.40	ChEMBL
β₃	ADRB3	Human	Adrenoceptors	A	pKi	5.31	5.31	5.31	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	5.55	5.55	5.55	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.08	7.08	7.08	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	7.30	7.30	7.30	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.37	6.37	6.37	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	8.40	8.40	8.40	Guide to Pharmacology
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.81	7.81	7.81	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.85	6.85	6.85	ChEMBL
5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pKi	7.60	8.00	8.40	Guide to Pharmacology
5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pKi	7.51	8.22	8.40	ChEMBL
5-HT_5A	5HT5A	Human	5-Hydroxytryptamine	A	pKi	6.70	6.70	6.70	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	6.25	6.25	6.25	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.53	6.53	6.53	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	6.37	6.37	6.37	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.72	6.72	6.72	ChEMBL

Showing 1 to 20 of 21 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pEC50	7.80	8.54	9.00	ChEMBL
CCR6	CCR6	Human	Chemokine	A	pIC50	4.63	4.63	4.63	ChEMBL

Showing 1 to 2 of 2 entries

tegaserod

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.