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SMILES Oc1ccc2c3c1O[C@@H]1[C@@]43CCN([C@H](C2)[C@]4(O)Cc2c1oc1c2cccc1)CC1CC1
InChIKey ZHVWWEYETMPAMX-IFKAHUTRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 10.89 10.89 10.89 ChEMBL
δ OPRD Human Opioid A pKi 10.0 10.0 10.0 Guide to Pharmacology
κ OPRK Human Opioid A pKi 8.4 8.4 8.4 Guide to Pharmacology
μ OPRM Human Opioid A pKi 7.9 7.9 7.9 Guide to Pharmacology
δ OPRD Rat Opioid A pKi 10.0 10.0 10.0 Guide to Pharmacology
δ OPRD Mouse Opioid A pKi 10.9 10.9 10.9 Guide to Pharmacology
κ OPRK Guinea pig Opioid A pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pIC50 6.16 6.16 6.16 ChEMBL