U92016A


SMILES CCCN([C@@H]1CCc2c(C1)c1cc([nH]c1cc2)C#N)CCC
InChIKey WDDZPZKGLZNGEH-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.7 9.7 9.7 Guide to Pharmacology
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.77 8.77 8.77 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 10.0 10.0 10.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database