UFP-505


SMILES O=C(NCc1ccccc1)CNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](Cc1c(C)cc(cc1C)O)N
InChIKey SYOVEDOWOXNOJG-SVBPBHIXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 9.8 9.8 9.8 ChEMBL
δ OPRD Human Opioid A pKi 10.51 10.51 10.51 ChEMBL
δ OPRD Human Opioid A pKi 9.82 9.82 9.82 Guide to Pharmacology
μ OPRM Human Opioid A pKi 9.8 9.8 9.8 ChEMBL
μ OPRM Human Opioid A pKi 7.79 7.79 7.79 Guide to Pharmacology
δ OPRD Mouse Opioid A pKd 9.25 9.27 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 8.57 8.57 8.57 ChEMBL