aspirin triggered lipoxin A4


SMILES CCCCC[C@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)O)O
InChIKey IXAQOQZEOGMIQS-JEWNPAEBSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 14
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKd 7.5 7.5 7.5 ChEMBL
A2B AA2BR Human Adenosine A pKi 7.2 7.2 7.2 ChEMBL
A3 AA3R Human Adenosine A pKi 6.0 6.0 6.0 ChEMBL
A3 AA3R Human Adenosine A pKd 5.8 5.8 5.8 ChEMBL
A2A AA2AR Human Adenosine A pKi 8.89 8.94 9.1 ChEMBL
A2A AA2AR Human Adenosine A pKd 9.2 9.2 9.2 ChEMBL
A1 AA1R Human Adenosine A pKd 7.0 7.0 7.0 ChEMBL
A1 AA1R Human Adenosine A pKi 7.17 7.17 7.17 ChEMBL
A1 AA1R Human Adenosine A pKi 7.17 7.17 7.17 Guide to Pharmacology
A2A AA2AR Human Adenosine A pKi 8.89 8.89 8.89 Guide to Pharmacology
A2B AA2BR Human Adenosine A pKi 7.2 7.2 7.2 Guide to Pharmacology
A3 AA3R Human Adenosine A pKi 6.0 6.0 6.0 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database