Anta Xv


SMILES CC(c1ccc(nc1)N1CCN(CC1)c1nnc(c2c1cccc2)Cc1ccccc1)(O)C
InChIKey KSWYJUIFHPSZOL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 4QIM

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Mouse Frizzled F pIC50 8.15 8.15 8.15 Guide to Pharmacology
SMO SMO Mouse Frizzled F pIC50 7.46 8.11 8.57 ChEMBL
SMO SMO Human Frizzled F pIC50 8.1 8.1 8.1 ChEMBL