Chembl10136

Chemical Properties

SMILES O=C(O)c1c(-c2ccc3c(c2)OCO3)c2cc(OCc3ccccc3)ccc2n1-c1ccc2c(c1)OCO2
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight 507.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey XJEFQVHNUODKBN-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETB EDNRB Human Endothelin A pIC50 4.85 4.85 4.85 ChEMBL
ETA EDNRA Human Endothelin A pIC50 5.89 5.89 5.89 ChEMBL