CHEMBL143027


SMILES O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2occc21
InChIKey RJXYBXCQVVCCAR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.61 6.61 6.61 ChEMBL
D1 DRD1 Rat Dopamine A pKi 7.54 7.54 7.54 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.02 8.02 8.02 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 4.74 5.54 6.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.95 8.11 8.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.79 7.79 7.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database