(R)-cetirizine [4228]



(R)-cetirizine


SMILES O=C(O)COCCN1CCN([C@H](c2ccccc2)c2ccc(Cl)cc2)CC1
InChIKey ZKLPARSLTMPFCP-OAQYLSRUSA-N

Chemical Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Log P 3.148
Molecular weight (Da) 388.2
Stereochemistry info full

Database connections

Ligand site mutations H1
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

(R)-cetirizine


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Ligand site mutations H1
GPCRdb related ligands

Compound is not listed as a drug.