kisspeptin-10 (Human) [4460]
kisspeptin-10 (Human)
| SMILES | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
| InChIKey | RITKWYDZSSQNJI-INXYWQKQSA-N |
| Sequence | YNWNSFGLRF |
| HELM | PEPTIDE1{Y.N.W.N.S.F.G.L.R.F.[am]}$$$$ |
Chemical Properties
| Hydrogen bond acceptors | 16 |
| Hydrogen bond donors | 18 |
| Rotatable bonds | 38 |
| Log P | -4.206 |
| Molecular weight (Da) | 1301.6 |
| Stereochemistry info | unspecified |
Database connections
| Structure pdb | 8ZJD |
| Model (AF2) | NPFF1 NPFF2 kisspeptin |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
kisspeptin-10 (Human)
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Endogenous |
| Approved drug | No |
Distribution across phases (no. indications)
Phase I
0
Phase II
0
Phase III
0
Phase IV
0
Database connections
| Structure pdb | 8ZJD |
| Model (AF2) | NPFF1 NPFF2 kisspeptin |