SETMELANOTIDE [484262]



SETMELANOTIDE

No image available
SMILES CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](C)NC1=O
InChIKey HDHDTKMUACZDAA-PHNIDTBTSA-N
Sequence None
HELM PEPTIDE1{[ac].R.C.[dA].H.[dF].R.W.C.[am]}$PEPTIDE1,PEPTIDE1,9:R3-3:R3$$$

Chemical Properties

Hydrogen bond acceptors 14
Hydrogen bond donors 17
Rotatable bonds 18
Log P -2.756
Molecular weight (Da) 1116.5

Database connections

GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

SETMELANOTIDE

No image available

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 1
Phase II 1
Phase III 0
Phase IV 2

Database connections


Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score