GPCRdb

CHEMBL105261

Agent/drug
Bioactivity

CHEMBL105261

SMILES	CCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
InChIKey	ORJIHHLJBCQRBS-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	286.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	6.14	6.14	6.14	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	6.14	6.14	6.14	ChEMBL
5-HT_1E	5HT1E	Human	5-Hydroxytryptamine	A	pKi	6.11	6.11	6.11	ChEMBL
5-HT_1F	5HT1F	Human	5-Hydroxytryptamine	A	pKi	8.26	8.26	8.26	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.47	5.47	5.47	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.51	6.51	6.51	ChEMBL
5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pKi	5.62	5.62	5.62	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	5.95	5.95	5.95	ChEMBL

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1F	5HT1F	Human	5-Hydroxytryptamine	A	pEC50	7.50	7.50	7.50	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL105261

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.