Ligand Data

Ligand

id 517
Name AZD1283
SMILES CCOC(=O)c1cc(C#N)c(nc1C)N1CCC(CC1)C(=O)NS(=O)(=O)Cc1ccccc1
InChIKey NEMHKCNXXRQYRF-UHFFFAOYSA-N
Type small-molecule
External Links
Structure pdb 4NTJ

Structure

Properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight 470.2


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
P2Y12 P2Y12 Human P2Y A (Rhodopsin) 9.0 655.9 3200.0